Technical Service - Atomatrix

Technical Service

CADD: Addressing Unmet Needs in Drug Development Cost Efficiency

Accelerate your drug discovery projects with our innovative CADD solution integrating AI and molecular dynamics.

Proposed Research Timeline

Contract
Signing
Hit Discovery 2–3 months
Hit-to-Lead 4–6 months
Lead Optimization 6–9 months
Contract
Completion
0
$150K
Upfront
1
$230K
Cumulative $380K
2
$230K
Cumulative $610K
3
$150K
Cumulative $760K
Hit Discovery
Discovery of Hit Scaffolds
IC/EC₅₀: sub-μM
or mutually agreed TPP criteria
1st Interim Report System setup results, 1st screening results
  • Literature-based target structure establishment
  • Literature-based reference compound selection
  • In silico model construction
    • Small-molecule/Peptide DB Adoption
    • Commercial/Virtual Library Screening
    • Molecular Docking
    • Molecular Dynamics Simulation
    • Binding Affinity Prediction
  • Commercial DB primary screening
  • Hit scaffold identification
Hit-to-Lead
Scaffold-based Ligand Optimization
IC/EC₅₀: ~1 μM
or mutually agreed TPP criteria
2nd Interim Report Lead candidate chemical library/DB, 2nd screening results
  • Scaffold structure-based lead generation
  • In silico lead candidate chemical library construction
  • Library-targeted 2nd lead virtual screening
  • Hit candidate identification
Lead Optimization
In vitro Data-based Optimization
IC/EC₅₀: ~100 nM
or mutually agreed TPP criteria
Final Report
  • Hit candidate in vitro data-based in silico model optimization
  • ADME/T-focused lead optimization
  • Final compound structure with optimized efficacy and structural novelty

B2C/B2B Customized Platform Business Model

Project-based Platform SW Service
  • Target-optimized SW license and technical support
  • Conditions optimized for client's drug IP strategy

✓ Customer loyalty based on SW platform utility

Target-specific Drug Discovery Service
  • Hit design for client's drug target (automatic SW acquisition with hit delivery)

✓ Atomatrix technology validation (PoC) effect